• PSMD9 Polyclonal Antibody
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Upingbio

YP-Ab-05217-100UL

PSMD9 Polyclonal Antibody

PSMD9 Polyclonal Antibody

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  • Gene Name: PSMD9
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120
  • Specificity: PSMD9 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. [provided b
  • Function: function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Belongs to the proteasome subunit p27 family.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Subunit of the modulator trimer complex that stimulates the association of the PA700 regulator with the catalytic 20S proteasome to form the ATP-dependent active 26S proteasome. P27 is associated not only with the modulator complex but also significantly with the 26S proteasome complex.,tissue specificity:Expressed in all tissues tested, highly expressed in liver and kidney.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA
  • Protein: 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27)
  • DA: 24kD
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