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Upingbio
SKU:YP-Ab-05192-100UL
NKAP Polyclonal Antibody
NKAP Polyclonal Antibody
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- Gene Name: NKAP
- Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90
- Specificity: NKAP Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010],
- Function: function:Regulator of TNF and IL-1 induced NF-kappa-B activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the UPF0396 family.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: NF-kappa-B-activating protein
- DA: 45kD
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