• WNK2 Polyclonal Antibody
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Upingbio

YP-Ab-05038-100UL

WNK2 Polyclonal Antibody

WNK2 Polyclonal Antibody

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  • Gene Name: WNK2 KIAA1760 PRKWNK2 SDCCAG43 P/OKcl.13
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 1120-1200
  • Specificity: WNK2 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-300. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
  • Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:Cys-224 is present instead of the conserved Lys which is expected to be an active site residue. Lys-207 appears to fulfill the required catalytic function.,cofactor:Magnesium.,enzyme regulation:Activation requires autophosphorylation of Ser-356. Phosphorylation of Ser-352 also promotes increased activity.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Predominantly expressed in heart, brain and colon.,
  • Species: Human;Mouse
  • Range: IHC;IF
  • Protein: Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Antigen NY-CO-43) (Protein kinase lysine-deficient 2) (Protein kinase with no lysine 2) (Serologically defined colon cancer antigen 43)
  • DA: 252kD
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