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Upingbio
SKU:YP-Ab-05002-100UL
LMTK1 Polyclonal Antibody
LMTK1 Polyclonal Antibody
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- Gene Name: AATK AATYK KIAA0641 LMR1 LMTK1
- Immunogen: Synthesized peptide derived from human protein . at AA range: 1110-1190
- Specificity: LMTK1 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
- Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May be involved in neuronal differentiation.,induction:Up-regulated during apoptosis.,PTM:Autophosphorylated. Phosphorylated by CDK5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly perinuclear.,subunit:Interacts with CDK5.,tissue specificity:Expressed in brain.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-bi
- DA: 151kD
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