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Upingbio
SKU:YP-Ab-04993-100UL
PGFRL Polyclonal Antibody
PGFRL Polyclonal Antibody
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- Gene Name: PDGFRL PRLTS
- Immunogen: Synthesized peptide derived from human protein . at AA range: 50-130
- Specificity: PGFRL Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008],
- Function: disease:Defects in PDGFRL are associated with colorectal cancer (CRC) [MIM:114500].,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in colon, lung and liver.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: Platelet-derived growth factor receptor-like protein (PDGFR-like protein) (PDGF receptor beta-like tumor suppressor)
- DA: 41kD
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