• HIPK1 Polyclonal Antibody
1 1

Upingbio

YP-Ab-04893-100UL

HIPK1 Polyclonal Antibody

HIPK1 Polyclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: HIPK1 KIAA0630 MYAK NBAK2
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 290-370
  • Specificity: HIPK1 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: homeodomain interacting protein kinase 1(HIPK1) Homo sapiens The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.,PTM:Autophosphorylated. Phosphorylated and activated by JNK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly nuclear.,subunit:Interacts with Nkx1-2 and Nkx2-5 (By similarity). Interacts with DAXX and TP53.,tissue specificity:Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA
  • Protein: Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)
  • DA: 133kD
View full details