• HO-1 Mouse mAb(Mix-mA)
1 1

Upingbio

YP-Ab-04799-10UL

HO-1 Mouse mAb(Mix-mA)

HO-1 Mouse mAb(Mix-mA)

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  • Reaction species: Human; Mouse;Rat
  • Gene Name: HMOX1 HO HO1
  • Protein name: HO-1
  • Molecular weight (DA): 28kD
  • Immunogen: Synthesized peptide derived from human HO-1
  • Specificity: This antibody detects endogenous levels of HO-1 at Human, Mouse,Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.39% sodium azide.
  • Source: Monoclonal, Mouse
  • Dilution ratio: IF 1:50-200 IHC-p1:50-200 ,WB 1:1000-2000
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Concentration: mg/ml
  • Storage: -20°C/1 year
  • Other Names: Heme oxygenase 1 (HO-1) (EC 1.14.99.3)
  • Background: heme oxygenase 1(HMOX1) Homo sapiens Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:Heme + 3 AH(2) + 3 O(2) = biliverdin + Fe(2+) + CO + 3 A + 3 H(2)O.,function:Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.,induction:Heme oxygenase 1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA.,similarity:Belongs to the heme oxygenase family.,
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