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Upingbio
SKU:YP-Ab-04794-10UL
HSP40 Mouse mAb(Mix-mA)
HSP40 Mouse mAb(Mix-mA)
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- Reaction species: Human; Mouse;Rat
- Gene Name: DNAJB1 DNAJ1 HDJ1 HSPF1
- Protein name: HSP40
- Molecular weight (DA): 40kD
- Immunogen: Synthesized peptide derived from human HSP40
- Specificity: This antibody detects endogenous levels of HSP40 at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.33% sodium azide.
- Source: Monoclonal, Mouse
- Dilution ratio: IHC-p1:50-200 ,WB 1:1000-2000
- Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Concentration: mg/ml
- Storage: -20°C/1 year
- Other Names: DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)
- Background: This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
- Function: function:Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP.,induction:By heat shock.,similarity:Contains 1 J domain.,subcellular location:Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.,subunit:Interacts with DNAJC3.,
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