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Upingbio
SKU:YP-Ab-04309-100UL
TFPI-2 Polyclonal Antibody
TFPI-2 Polyclonal Antibody
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- Gene Name: TFPI2
- Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human TFPI2. AA range:186-235
- Specificity: TFPI-2 Polyclonal Antibody detects endogenous levels of TFPI-2 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: TFPI2; Tissue factor pathway inhibitor 2; TFPI-2; Placental protein 5; PP5
- Background: This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
- Function: domain:This inhibitor contains three inhibitory domains.,function:May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,similarity:Contains 3 BPTI/Kunitz inhibitor domains.,tissue specificity:Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: Tissue factor pathway inhibitor 2
- DA: 13kD
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