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Upingbio

SKU:YP-Ab-04289-100UL

β-1,3-Gal-TL Polyclonal Antibody

β-1,3-Gal-TL Polyclonal Antibody

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  • Gene Name: B3GALTL
  • Immunogen: The antiserum was produced against synthesized peptide derived from human B3GALTL. AA range:449-498
  • Specificity: β-1,3-Gal-TL Polyclonal Antibody detects endogenous levels of β-1,3-Gal-TL protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: B3GALTL; B3GTL; Beta-1; 3-glucosyltransferase; Beta3Glc-T; Beta-3-glycosyltransferase-like
  • Background: The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009],
  • Function: disease:Defects in B3GALTL are the cause of Peters-plus syndrome (PPS) [MIM:261540]. PPS is an autosomal recessive disorder characterized by anterior eye-chamber abnormalities, disproportionate short stature, developmental delay, characteristic craniofacial features, cleft lip and/or palate.,function:O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:Widely expressed, with highest levels in testis and uterus.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Beta-1,3-glucosyltransferase
  • DA: 57kD
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