• TIMAP Polyclonal Antibody
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Upingbio

YP-Ab-04244-100UL

TIMAP Polyclonal Antibody

TIMAP Polyclonal Antibody

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  • Gene Name: PPP1R16B
  • Immunogen: The antiserum was produced against synthesized peptide derived from human PPP1R16B. AA range:364-413
  • Specificity: TIMAP Polyclonal Antibody detects endogenous levels of TIMAP protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PPP1R16B; ANKRD4; KIAA0823; Protein phosphatase 1 regulatory inhibitor subunit 16B; Ankyrin repeat domain-containing protein 4; CAAX box protein TIMAP; TGF-beta-inhibited membrane-associated protein; hTIMAP
  • Background: The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015],
  • Function: function:May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.,induction:Inhibited by TGF-beta1.,similarity:Contains 5 ANK repeats.,subunit:Binds PP1.,tissue specificity:Highly expressed in vascular endothelium, CNS, lung, spleen, kidney and testis.,
  • Species: Human;Mouse
  • Range: WB;IHC
  • Protein: Protein phosphatase 1 regulatory inhibitor subunit 16B
  • DA: 64kD
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