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Upingbio
SKU:YP-Ab-04198-100UL
Septin 3 Polyclonal Antibody
Septin 3 Polyclonal Antibody
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- Gene Name: 45172
- Immunogen: The antiserum was produced against synthesized peptide derived from human SEPT3. AA range:136-185
- Specificity: Septin 3 Polyclonal Antibody detects endogenous levels of Septin 3 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: SEPT3; SEP3; Neuronal-specific septin-3
- Background: septin 3(SEPT3) Homo sapiens This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
- Function: function:Involved in cytokinesis .,induction:Up-regulated during neuronal differentiation.,PTM:Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.,similarity:Belongs to the septin family.,subcellular location:Localizes in synaptosomes at dendritic synapses of neurons. Localizes within presynaptic terminals of neurons.,subunit:May assemble into a multicomponent structure.,tissue specificity:Brain specific.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA;IHC
- Protein: Neuronal-specific septin-3
- DA: 41kD
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