• RGS12 Polyclonal Antibody
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Upingbio

YP-Ab-04121-100UL

RGS12 Polyclonal Antibody

RGS12 Polyclonal Antibody

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  • Gene Name: RGS12
  • Immunogen: The antiserum was produced against synthesized peptide derived from human RGS12. AA range:141-190
  • Specificity: RGS12 Polyclonal Antibody detects endogenous levels of RGS12 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: RGS12; Regulator of G-protein signaling 12; RGS12
  • Background: This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008],
  • Function: function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 GoLoco domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PID domain.,similarity:Contains 1 RGS domain.,similarity:Contains 2 RBD (Ras-binding) domains.,tissue specificity:Isoform 3 is brain specific.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA;IHC
  • Protein: Regulator of G-protein signaling 12
  • DA: 160kD
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