• REPS1 Polyclonal Antibody
1 1

Upingbio

YP-Ab-04116-100UL

REPS1 Polyclonal Antibody

REPS1 Polyclonal Antibody

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  • Gene Name: REPS1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human REPS1. AA range:597-646
  • Specificity: REPS1 Polyclonal Antibody detects endogenous levels of REPS1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: REPS1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1
  • Background: This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
  • Function: function:May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.,PTM:EGF stimulates phosphorylation on Tyr-residues.,similarity:Contains 1 EF-hand domain.,similarity:Contains 1 EH domain.,subunit:Homodimer (Potential). Interacts with RAB11FIP2. Interacts with RALBP1, CRK and GRB2. Binding to RALBP1 does not affect its Ral-binding activity. Forms a complex with the SH3 domains of CRK and GRB2 which may link it to an EGF-responsive tyrosine kinase.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA;IHC
  • Protein: RalBP1-associated Eps domain-containing protein 1
  • DA: 80kD
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