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Upingbio
SKU:YP-Ab-04097-100UL
PPP1R14D Polyclonal Antibody
PPP1R14D Polyclonal Antibody
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- Gene Name: PPP1R14D
- Immunogen: The antiserum was produced against synthesized peptide derived from human PPP1R14D. AA range:66-115
- Specificity: PPP1R14D Polyclonal Antibody detects endogenous levels of PPP1R14D protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: PPP1R14D; GBPI; Protein phosphatase 1 regulatory subunit 14D; Gastrointestinal and brain-specific PP1-inhibitory protein 1; GBPI-1
- Background: Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010],
- Function: function:Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.,PTM:Phosphorylated on several residues.,similarity:Belongs to the PP1 inhibitor family.,tissue specificity:Detected in colon, intestine, kidney and brain cortex.,
- Species: Human;Rat;Mouse;
- Range: WB;IHC;IF;ELISA
- Protein: Protein phosphatase 1 regulatory subunit 14D
- DA: 24kD
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