• ME2 Polyclonal Antibody
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Upingbio

YP-Ab-03952-100UL

ME2 Polyclonal Antibody

ME2 Polyclonal Antibody

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  • Gene Name: ME2
  • Immunogen: The antiserum was produced against synthesized peptide derived from human ME2. AA range:201-250
  • Specificity: ME2 Polyclonal Antibody detects endogenous levels of ME2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ME2; NAD-dependent malic enzyme; mitochondrial; NAD-ME; Malic enzyme 2
  • Background: This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009],
  • Function: catalytic activity:(S)-malate + NAD(+) = pyruvate + CO(2) + NADH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,enzyme regulation:Subject to allosteric activation by fumarate.,miscellaneous:This isoenzyme can also use NADP(+) but is more effective with NAD(+).,similarity:Belongs to the malic enzymes family.,subunit:Homotetramer.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: NAD-dependent malic enzyme mitochondrial
  • DA: 65kD
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