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Upingbio
SKU:YP-Ab-03857-100UL
Eps8L2 Polyclonal Antibody
Eps8L2 Polyclonal Antibody
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- Gene Name: EPS8L2
- Immunogen: The antiserum was produced against synthesized peptide derived from human ES8L2. AA range:1-50
- Specificity: Eps8L2 Polyclonal Antibody detects endogenous levels of Eps8L2 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: EPS8L2; EPS8R2; PP13181; Epidermal growth factor receptor kinase substrate 8-like protein 2; EPS8-like protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8-related protein 2
- Background: This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008],
- Function: function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 PID domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in fibroblasts and placenta.,
- Species: Human;Mouse
- Range: WB;IHC;IF;ELISA
- Protein: Epidermal growth factor receptor kinase substrate 8-like protein 2
- DA: 81kD
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