• Dvl-2 Polyclonal Antibody
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Upingbio

YP-Ab-03829-100UL

Dvl-2 Polyclonal Antibody

Dvl-2 Polyclonal Antibody

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  • Gene Name: DVL2
  • Immunogen: Synthesized peptide derived from Dvl-2 . at AA range: 670-750
  • Specificity: Dvl-2 Polyclonal Antibody detects endogenous levels of Dvl-2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: DVL2; Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2
  • Background: This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008],
  • Function: function:May play a role in the signal transduction pathway mediated by multiple Wnt genes.,PTM:Phosphorylated.,similarity:Belongs to the DSH family.,similarity:Contains 1 DEP domain.,similarity:Contains 1 DIX domain.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Interacts through its PDZ domain with the C-terminal regions of VANGL1 and VANGL2 (By similarity). Interacts with DIXDC1 and Rac.,
  • Species: Human;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: Segment polarity protein dishevelled homolog DVL-2
  • DA: 80kD
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