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SKU:YP-Ab-03816-100UL
DnaJB4 Polyclonal Antibody
DnaJB4 Polyclonal Antibody
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- Gene Name: DNAJB4
- Immunogen: The antiserum was produced against synthesized peptide derived from human DNAJB4. AA range:91-140
- Specificity: DnaJB4 Polyclonal Antibody detects endogenous levels of DnaJB4 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: DNAJB4; DNAJW; HLJ1; DnaJ homolog subfamily B member 4; Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein
- Background: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
- Function: induction:By heat shock.,similarity:Contains 1 J domain.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: DnaJ homolog subfamily B member 4
- DA: 38kD
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