• Defensin α1 Polyclonal Antibody
1 1

Upingbio

YP-Ab-03812-100UL

Defensin α1 Polyclonal Antibody

Defensin α1 Polyclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: DEFA1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human Defensin alpha1. AA range:3-52
  • Specificity: Defensin α1 Polyclonal Antibody detects endogenous levels of Defensin α1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: DEFA1; DEF1; DEFA2; MRS; DEFA1B; Neutrophil defensin 1; Defensin; alpha 1; HNP-1; HP-1; HP1
  • Background: defensin alpha 1(DEFA1) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014],
  • Function: function:Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.,similarity:Belongs to the alpha-defensin family.,subunit:Dimer.,
  • Species: Human;Rat;Mouse;
  • Range: IHC;IF;ELISA
  • Protein: Neutrophil defensin 1
  • DA: 11kD
View full details