• CD172b Polyclonal Antibody
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Upingbio

YP-Ab-03749-100UL

CD172b Polyclonal Antibody

CD172b Polyclonal Antibody

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  • Gene Name: SIRPB1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human SIRPB1. AA range:231-280
  • Specificity: CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: SIRPB1; Signal-regulatory protein beta-1; SIRP-beta-1; CD172 antigen-like family member B; CD antigen CD172b
  • Background: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],
  • Function: function:Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.,function:Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK.,PTM:N-glycosylated.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C1-type (immunoglobulin-like) domains.,subunit:Interacts with TYROBP. This interaction results in the recruitment of SYK.,tissue specificity:Detected in monocytes and dendritic cells.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Signal-regulatory protein beta-1
  • DA: 48kD
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