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SKU:YP-Ab-03734-100UL
Ataxin-2L Polyclonal Antibody
Ataxin-2L Polyclonal Antibody
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- Gene Name: ATXN2L
- Immunogen: The antiserum was produced against synthesized peptide derived from human ATXN2L. AA range:571-620
- Specificity: Ataxin-2L Polyclonal Antibody detects endogenous levels of Ataxin-2L protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: ATXN2L; A2D; A2LG; A2LP; A2RP; Ataxin-2-like protein; Ataxin-2 domain protein; Ataxin-2-related protein
- Background: This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
- Function: PTM:Arg-361 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Thrombopoietin triggers the phosphorylation on tyrosine residues in a way that is dependent on MPL C-terminal domain.,sequence caution:Exon duplication.,similarity:Belongs to the ataxin-2 family.,subunit:Interacts with MPL/TPOR and EPOR and dissociates after ligand stimulation.,tissue specificity:Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis. Constitutively associated with MPL and EPOR in hematopoietic cells.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: Ataxin-2-like protein
- DA: 113kD
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