• ARPP-21 Polyclonal Antibody
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Upingbio

YP-Ab-03717-100UL

ARPP-21 Polyclonal Antibody

ARPP-21 Polyclonal Antibody

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  • Gene Name: ARPP21
  • Immunogen: The antiserum was produced against synthesized peptide derived from human ARPP21. AA range:211-260
  • Specificity: ARPP-21 Polyclonal Antibody detects endogenous levels of ARPP-21 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ARPP21; TARPP; cAMP-regulated phosphoprotein 21; ARPP-21; Thymocyte cAMP-regulated phosphoprotein
  • Background: This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],
  • Function: function:Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.,PTM:Isoform 1 is methylated by CARM1 in immature thymocytes.,PTM:Phosphorylation at Ser-56 favors interaction with CALM1.,similarity:Contains 1 R3H domain.,subunit:Interacts with CALM1.,tissue specificity:Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level).,
  • Species: Human;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: cAMP-regulated phosphoprotein 21
  • DA: 80kD
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