• AIM2 Polyclonal Antibody
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Upingbio

YP-Ab-03685-100UL

AIM2 Polyclonal Antibody

AIM2 Polyclonal Antibody

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  • Gene Name: AIM2
  • Immunogen: The antiserum was produced against synthesized peptide derived from human AIM2. AA range:51-100
  • Specificity: AIM2 Polyclonal Antibody detects endogenous levels of AIM2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2
  • Background: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008],
  • Function: disease:Defects in AIM2 may be a cause of microsatellite unstable colon cancers.,function:Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.,induction:By interferon gamma.,similarity:Belongs to the HIN-200 family.,similarity:Contains 1 DAPIN domain.,similarity:Contains 1 HIN-200 domain.,subunit:Homodimer.,tissue specificity:Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.,
  • Species: Human; Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Interferon-inducible protein AIM2
  • DA: 39kD
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