• Rictor (phospho-Thr1135) rabbit pAb
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Upingbio

YP-Ab-03639-100UL

Rictor (phospho-Thr1135) rabbit pAb

Rictor (phospho-Thr1135) rabbit pAb

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  • Gene Name: RICTOR KIAA1999
  • Immunogen: Synthesized phosho peptide around human Rictor (Thr1135)
  • Specificity: This antibody detects endogenous levels of Human Mouse Rictor (phospho-Thr1135)
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
  • Background: RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],
  • Function: function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2.,
  • Species: Human;Mouse
  • Range: WB;IHC
  • Protein: Rictor (Thr1135)
  • DA: 190kD
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