• Gab1 Rabbit Polyclonal Antibody
1 1

Upingbio

YP-Ab-03503-100UL

Gab1 Rabbit Polyclonal Antibody

Gab1 Rabbit Polyclonal Antibody

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  • Gene Name: GAB1
  • Immunogen: Recombinant Protein of Gab1
  • Specificity: The antibody detects endogenous Gab1 protein
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-300. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: GRB2-associated-binding protein 1 (GRB2-associated binder 1;Growth factor receptor bound protein 2-associated protein 1)
  • Background: GRB2 associated binding protein 1(GAB1) Homo sapiens The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
  • Function: function:Probably involved in EGF and insulin receptor signaling.,PTM:Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.,similarity:Belongs to the GAB family.,similarity:Contains 1 PH domain.,subunit:Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2.,
  • Species: Human;Mouse;Rat
  • Range: IHC;IF
  • Protein: GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
  • DA: 76kD
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