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Upingbio

SKU:YP-Ab-03200-100UL

Troponin I-C Polyclonal Antibody

Troponin I-C Polyclonal Antibody

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  • Gene Name: TNNI3
  • Immunogen: The antiserum was produced against synthesized peptide derived from mouse TNNI3. AA range:5-54
  • Specificity: Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I
  • Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
  • Species: Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Troponin I cardiac muscle
  • DA: 28kD
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