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Upingbio
SKU:YP-Ab-03189-100UL
SPZ1 Polyclonal Antibody
SPZ1 Polyclonal Antibody
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- Gene Name: SPZ1
- Immunogen: The antiserum was produced against synthesized peptide derived from human SPZ1. AA range:111-160
- Specificity: SPZ1 Polyclonal Antibody detects endogenous levels of SPZ1 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: SPZ1; TSP1; Spermatogenic leucine zipper protein 1; Testis-specific protein 1; Testis-specific protein NYD-TSP1
- Background: This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011],
- Function: function:Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.,PTM:Phosphorylated by ERK1 and ERK2.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with PPP1CC isoform gamma-2.,tissue specificity:Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.,
- Species: Human;Rat;Mouse;
- Range: IHC;IF;WB;ELISA
- Protein: Spermatogenic leucine zipper protein 1
- DA: 133kD
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