• Involucrin Polyclonal Antibody
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Upingbio

YP-Ab-03141-100UL

Involucrin Polyclonal Antibody

Involucrin Polyclonal Antibody

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  • Gene Name: IVL
  • Immunogen: The antiserum was produced against synthesized peptide derived from human Involucrin. AA range:536-585
  • Specificity: Involucrin Polyclonal Antibody detects endogenous levels of Involucrin protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: IVL; Involucrin
  • Background: involucrin(IVL) Homo sapiens Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008],
  • Function: function:Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.,PTM:Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide.,similarity:Belongs to the involucrin family.,subcellular location:Constituent of the scaffolding of the cornified envelope.,subunit:Directly or indirectly cross-linked to cornifelin (CNFN).,tissue specificity:Keratinocytes of epidermis and other stratified squamous epithelia.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Involucrin
  • DA: 68kD
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