• Calgizzarin Polyclonal Antibody
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YP-Ab-03092-100UL

Calgizzarin Polyclonal Antibody

Calgizzarin Polyclonal Antibody

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  • Gene Name: S100A11
  • Immunogen: Synthesized peptide derived from Calgizzarin . at AA range: 30-110
  • Specificity: Calgizzarin Polyclonal Antibody detects endogenous levels of Calgizzarin protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: S100A11; MLN70; S100C; Protein S100-A11; Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70; Protein S100-C; S100 calcium-binding protein A11
  • Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008],
  • Function: function:Facilitates the differentiation and the cornification of keratinocytes.,miscellaneous:Binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins.,PTM:Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer; disulfide-linked.,
  • Species: Human;Mouse;Rat
  • Range: IHC;IF;ELISA
  • Protein: Protein S100-A11
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