• UBE4A Polyclonal Antibody
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Upingbio

YP-Ab-02849-100UL

UBE4A Polyclonal Antibody

UBE4A Polyclonal Antibody

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  • Gene Name: UBE4A
  • Immunogen: Synthesized peptide derived from the N-terminal region of human UBE4A.
  • Specificity: UBE4A Polyclonal Antibody detects endogenous levels of UBE4A protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A
  • Background: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011],
  • Function: function:Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the ubiquitin conjugation factor E4 family.,similarity:Contains 1 U-box domain.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Ubiquitin conjugation factor E4 A
  • DA: 122kD
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