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Upingbio
SKU:YP-Ab-02828-100UL
USP15 Polyclonal Antibody
USP15 Polyclonal Antibody
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- Gene Name: USP15
- Immunogen: The antiserum was produced against synthesized peptide derived from human USP15. AA range:81-130
- Specificity: USP15 Polyclonal Antibody detects endogenous levels of USP15 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: USP15; KIAA0529; Ubiquitin carboxyl-terminal hydrolase 15; Deubiquitinating enzyme 15; Ubiquitin thioesterase 15; Ubiquitin-specific-processing protease 15; Unph-2; Unph4
- Background: This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011],
- Function: catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 DUSP domain.,tissue specificity:Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: Ubiquitin carboxyl-terminal hydrolase 15
- DA: 115kD
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