• SENP3 Polyclonal Antibody
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Upingbio

YP-Ab-02780-100UL

SENP3 Polyclonal Antibody

SENP3 Polyclonal Antibody

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  • Gene Name: SENP3
  • Immunogen: The antiserum was produced against synthesized peptide derived from human SENP3. AA range:10-59
  • Specificity: SENP3 Polyclonal Antibody detects endogenous levels of SENP3 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: SENP3; SSP3; SUSP3; Sentrin-specific protease 3; SUMO-1-specific protease 3; Sentrin/SUMO-specific protease SENP3
  • Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],
  • Function: function:Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.,similarity:Belongs to the peptidase C48 family.,subunit:Binds to UBL1 and SMT3H1.,
  • Species: Human;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: Sentrin-specific protease 3
  • DA: 80kD
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