• PIG-X Polyclonal Antibody
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Upingbio

YP-Ab-02754-100UL

PIG-X Polyclonal Antibody

PIG-X Polyclonal Antibody

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  • Gene Name: PIGX
  • Immunogen: The antiserum was produced against synthesized peptide derived from human PIGX. AA range:183-232
  • Specificity: PIG-X Polyclonal Antibody detects endogenous levels of PIG-X protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PIGX; Phosphatidylinositol-glycan biosynthesis class X protein; PIG-X
  • Background: This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
  • Function: function:Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,PTM:N-glycosylated.,sequence caution:Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon.,similarity:Belongs to the PIGX family.,subunit:Interacts with PIGM.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Phosphatidylinositol-glycan biosynthesis class X protein
  • DA: 26kD
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