• ME3 Polyclonal Antibody
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Upingbio

YP-Ab-02674-100UL

ME3 Polyclonal Antibody

ME3 Polyclonal Antibody

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  • Gene Name: ME3
  • Immunogen: The antiserum was produced against synthesized peptide derived from human ME3. AA range:545-594
  • Specificity: ME3 Polyclonal Antibody detects endogenous levels of ME3 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ME3; NADP-dependent malic enzyme; mitochondrial; NADP-ME; Malic enzyme 3
  • Background: Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,similarity:Belongs to the malic enzymes family.,tissue specificity:Expressed predominantly in organs with a low-division rate.,
  • Species: Human;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: NADP-dependent malic enzyme mitochondrial
  • DA: 67kD
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