• GGH Polyclonal Antibody
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Upingbio

YP-Ab-02640-100UL

GGH Polyclonal Antibody

GGH Polyclonal Antibody

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  • Gene Name: GGH
  • Immunogen: The antiserum was produced against synthesized peptide derived from human GGH. AA range:251-300
  • Specificity: GGH Polyclonal Antibody detects endogenous levels of GGH protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: GGH; Gamma-glutamyl hydrolase; Conjugase; GH; Gamma-Glu-X carboxypeptidase
  • Background: This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:Hydrolysis of a gamma-glutamyl bond.,function:Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.,similarity:Belongs to the peptidase C26 family.,similarity:Contains 1 gamma-glutamyl hydrolase domain.,subcellular location:While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Gamma-glutamyl hydrolase
  • DA: 36kD
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