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Upingbio
SKU:YP-Ab-02554-100UL
CROT Polyclonal Antibody
CROT Polyclonal Antibody
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- Gene Name: CROT
- Immunogen: Synthesized peptide derived from CROT . at AA range: 190-270
- Specificity: CROT Polyclonal Antibody detects endogenous levels of CROT protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: CROT; COT; Peroxisomal carnitine O-octanoyltransferase; COT
- Background: This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],
- Function: catalytic activity:Octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine.,function:Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the carnitine/choline acetyltransferase family.,subunit:Monomer.,
- Species: Human;Mouse;Rat
- Range: IHC;IF;ELISA
- Protein: Peroxisomal carnitine O-octanoyltransferase
- DA: 72kD
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