• cPLA2-δ Polyclonal Antibody
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Upingbio

YP-Ab-02552-100UL

cPLA2-δ Polyclonal Antibody

cPLA2-δ Polyclonal Antibody

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  • Gene Name: PLA2G4D
  • Immunogen: The antiserum was produced against synthesized peptide derived from human PLA2G4D. AA range:531-580
  • Specificity: cPLA2-δ Polyclonal Antibody detects endogenous levels of cPLA2-δ protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PLA2G4D; Cytosolic phospholipase A2 delta; cPLA2-delta; Phospholipase A2 group IVD
  • Background: The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).[supplied by OMIM, Jun 2009],
  • Function: catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,domain:The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+).,enzyme regulation:Stimulated by cytosolic Ca(2+).,function:Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Not arachidonic acid-specific but has linoleic acid-specific activity. May play a role in inflammation in psoriatic lesions.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PLA2c domain.,subcellular location:Translocates to membrane vesicles in a calcium-dependent fashion. Translocates to perinuclear regions upon ionomycin stimulation.,tissue specificity:Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in ot
  • Species: Human;Rat;Mouse;
  • Range: IHC;IF;ELISA
  • Protein: Cytosolic phospholipase A2 delta
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