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Upingbio
SKU:YP-Ab-02521-100UL
Calpain 11 Polyclonal Antibody
Calpain 11 Polyclonal Antibody
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- Gene Name: CAPN11
- Immunogen: The antiserum was produced against synthesized peptide derived from human CAPN11. AA range:401-450
- Specificity: Calpain 11 Polyclonal Antibody detects endogenous levels of Calpain 11 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: CAPN11; Calpain-11; Calcium-activated neutral proteinase 11; CANP 11
- Background: Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008],
- Function: catalytic activity:Broad endopeptidase specificity.,function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 2 EF-hand domains.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,tissue specificity:Highest expression in testis.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: Calpain-11
- DA: 81kD
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