• ADAMTS-19 Polyclonal Antibody
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Upingbio

YP-Ab-02482-100UL

ADAMTS-19 Polyclonal Antibody

ADAMTS-19 Polyclonal Antibody

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  • Gene Name: ADAMTS19
  • Immunogen: The antiserum was produced against synthesized peptide derived from human ADAMTS19. AA range:251-300
  • Specificity: ADAMTS-19 Polyclonal Antibody detects endogenous levels of ADAMTS-19 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: ADAMTS19; A disintegrin and metalloproteinase with thrombospondin motifs 19; ADAM-TS 19; ADAM-TS19; ADAMTS-19
  • Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008],
  • Function: cofactor:Binds 1 zinc ion per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 peptidase M12B domain.,similarity:Contains 1 PLAC domain.,similarity:Contains 5 TSP type-1 domains.,tissue specificity:Expressed in fetal lung, but not in any adult tissues examined. Expression was detected in an osteosarcoma cDNA library.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: A disintegrin and metalloproteinase with thrombospondin motifs 19
  • DA: 140kD
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