• PLC β3 (phospho Ser537) Polyclonal Antibody
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Upingbio

YP-Ab-02413-100UL

PLC β3 (phospho Ser537) Polyclonal Antibody

PLC β3 (phospho Ser537) Polyclonal Antibody

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  • Gene Name: PLCB3
  • Immunogen: The antiserum was produced against synthesized peptide derived from human PLC beta3 around the phosphorylation site of Ser537. AA range:503-552
  • Specificity: Phospho-PLC β3 (S537) Polyclonal Antibody detects endogenous levels of PLC β3 protein only when phosphorylated at S537.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PLCB3; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-3; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3
  • Background: This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
  • Function: catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,subunit:Interacts with SHANK2 (By similarity). Interacts with LPAR2.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  • DA: 150kD
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