• CATB (Cleaved-Asn126) rabbit pAb
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YP-Ab-02303-100UL

CATB (Cleaved-Asn126) rabbit pAb

CATB (Cleaved-Asn126) rabbit pAb

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  • Gene Name: CTSB CPSB
  • Immunogen: Synthesized peptide derived from human CATB (Cleaved-Asn126)
  • Specificity: This antibody detects endogenous levels of Human CATB (Cleaved-Asn126, protein was cleaved amino acid sequence between 126-127 )
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Cathepsin B (EC 3.4.22.1;APP secretase;APPS;Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]
  • Background: catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.,function:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.,similarity:Belongs to the peptidase C1 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.,
  • Function: proteolysis, response to wounding, regulation of cell death, regulation of apoptosis, regulation of programmed cell death,
  • Species: Human;Rat;Mouse;
  • Range: WB; ELISA
  • Protein: CATB (Cleaved-Asn126)
  • DA: 15 37kD
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