• HMG-1 Polyclonal Antibody
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Upingbio

YP-Ab-02250-100UL

HMG-1 Polyclonal Antibody

HMG-1 Polyclonal Antibody

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  • Gene Name: HMGB1
  • Immunogen: Synthesized peptide derived from the N-terminal region of human HMG-1.
  • Specificity: HMG-1 Polyclonal Antibody detects endogenous levels of HMG-1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
  • Background: This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015],
  • Function: function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
  • Species: Human;Mouse;Rat
  • Range: IF;WB;IHC;ELISA
  • Protein: High mobility group protein B1
  • DA: about 30kd
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