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SKU:YP-Ab-02229-100UL
KLF12 Polyclonal Antibody
KLF12 Polyclonal Antibody
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- Gene Name: KLF12
- Immunogen: Synthesized peptide derived from the Internal region of human KLF12.
- Specificity: KLF12 Polyclonal Antibody detects endogenous levels of KLF12 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: KLF12; AP2REP; HSPC122; Krueppel-like factor 12; Transcriptional repressor AP-2rep
- Background: Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
- Function: function:Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,
- Species: Human;Mouse
- Range: WB;IHC;IF;ELISA
- Protein: Krueppel-like factor 12
- DA: 44kD
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