• XRN2 Polyclonal Antibody
1 1

Upingbio

YP-Ab-02157-100UL

XRN2 Polyclonal Antibody

XRN2 Polyclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: XRN2
  • Immunogen: The antiserum was produced against synthesized peptide derived from human XRN2. AA range:81-130
  • Specificity: XRN2 Polyclonal Antibody detects endogenous levels of XRN2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: XRN2; 5'-3' exoribonuclease 2; DHM1-like protein; DHP protein
  • Background: This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
  • Function: catalytic activity:Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.,function:Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription.,similarity:Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.,similarity:Contains 1 CCHC-type zinc finger.,tissue specificity:Expressed in the spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocytes, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Isoform 2
  • Species: Human;Mouse;Monkey
  • Range: WB;IHC;IF;ELISA
  • Protein: 5'-3' exoribonuclease 2
  • DA: 108kD
View full details