• TP1 Polyclonal Antibody
1 1

Upingbio

YP-Ab-02127-100UL

TP1 Polyclonal Antibody

TP1 Polyclonal Antibody

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  • Gene Name: TEP1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human TEP1. AA range:171-220
  • Specificity: TP1 Polyclonal Antibody detects endogenous levels of TP1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: TEP1; TLP1; TP1; Telomerase protein component 1; Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog
  • Background: This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
  • Function: function:Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.,similarity:Contains 1 NACHT domain.,similarity:Contains 1 TROVE domain.,similarity:Contains 21 WD repeats.,similarity:Contains 4 TEP1 N-terminal repeats.,subunit:Component of the telomerase holoenzyme complex at least composed of TERT, DKC1, WDR79/TCAB1, NOP10, NHP2, GAR1, TEP1, EST1A, POT1 and a telomerase RNA template component (TERC). Component of the vault ribonucleoprotein particle, at least composed of MVP, PARP4 and one or more vault RNAs (vRNAs). Binds to VAULTRC1, VAULTRC2 and VAULTRC4/hvg4 vRNAs.,tissue
  • Species: Human;Rat;Mouse;
  • Range: IHC;IF;ELISA
  • Protein: Telomerase protein component 1
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