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SKU:YP-Ab-02029-100UL
Sox-12 Polyclonal Antibody
Sox-12 Polyclonal Antibody
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- Gene Name: SOX12
- Immunogen: The antiserum was produced against synthesized peptide derived from human SOX12. AA range:71-120
- Specificity: Sox-12 Polyclonal Antibody detects endogenous levels of Sox-12 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: SOX12; SOX22; Transcription factor SOX-12; Protein SOX-22
- Background: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013],
- Function: function:Binds to the sequence 5'-AACAAT-3'.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive.,
- Species: Human;Mouse
- Range: IHC;IF;ELISA
- Protein: Transcription factor SOX-12
- DA: 34kD
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