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Upingbio
SKU:YP-Ab-01960-100UL
PRPF18 Polyclonal Antibody
PRPF18 Polyclonal Antibody
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- Gene Name: PRPF18
- Immunogen: The antiserum was produced against synthesized peptide derived from human PRPF18. AA range:182-231
- Specificity: PRPF18 Polyclonal Antibody detects endogenous levels of PRPF18 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18
- Background: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008],
- Function: function:Participates in the second step of pre-mRNA splicing.,similarity:Belongs to the PRP18 family.,subcellular location:Colocalizes with spliceosomal snRNPs.,subunit:Heterodimer with PPIH. Interacts with PRPF4 and with the spliceosome. Part of a complex containing U4/U6 snRNPs.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA;IHC
- Protein: Pre-mRNA-splicing factor 18
- DA: 40kD
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