• PHF1 Polyclonal Antibody
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Upingbio

YP-Ab-01939-100UL

PHF1 Polyclonal Antibody

PHF1 Polyclonal Antibody

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  • Gene Name: PHF1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human PHF1. AA range:345-394
  • Specificity: PHF1 Polyclonal Antibody detects endogenous levels of PHF1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PHF1; PCL1; PHD finger protein 1; Protein PHF1; Polycomb-like protein 1; hPCl1
  • Background: This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
  • Function: function:Transcriptional repressor. May promote methylation of histone H3 on 'Lys-27' by the PRC2/EED-EZH2 complex.,similarity:Contains 2 PHD-type zinc fingers.,subcellular location:Localizes specifically to the promoters of numerous target genes.,subunit:Interacts with CHMP1 (By similarity). Interacts with the PRC2 complex.,tissue specificity:Highest levels in heart, skeletal muscle, and pancreas, lower levels in brain, placenta, lung, liver and kidney.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: PHD finger protein 1
  • DA: 62kD
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