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Upingbio

SKU:YP-Ab-01913-100UL

NPAS4 Polyclonal Antibody

NPAS4 Polyclonal Antibody

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  • Gene Name: NPAS4
  • Immunogen: The antiserum was produced against synthesized peptide derived from human NPAS4. AA range:603-652
  • Specificity: NPAS4 Polyclonal Antibody detects endogenous levels of NPAS4 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: NPAS4; BHLHE79; NXF; PASD10; Neuronal PAS domain-containing protein 4; Neuronal PAS4; Class E basic helix-loop-helix protein 79; bHLHe79; HLH-PAS transcription factor NXF; PAS domain-containing protein 10
  • Background: NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008],
  • Function: function:Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT.,tissue specificity:Brain.,
  • Species: Human;Mouse;Rat
  • Range: IHC;IF;ELISA
  • Protein: Neuronal PAS domain-containing protein 4
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